Ezra E. Fitz  began his literary life at Princeton University, studying under the tutelage of James Irby, C.K. Williams, and Jonathan Galassi.  His senior thesis was described by Robert Fagles as "a heartening manifesto" on the art of translation.  

Since then, he has focused his attention on contemporary Latin American literature, including the controversial Crack generation and the McOndo movement.  His translations have been praised by The New York Times, The Washington Post, The New Yorker, and The Believer, among other publications.

His work has appeared in The Boston Review, Harper's Magazine, and Words Without Borders, he has been awarded grants from the United Nations Educational, Scientific, and Cultural Organization (UNESCO) and the Mexican National Fund for Culture and Arts (FONCA), and he was a 2010 Resident at the Banff International Literary Translation Centre in Alberta, Canada.

Fitz has also authored a novel of his own set in the New York neighborhoods of Morningside Heights and Crown Heights.